Dr. Michael Wheeler PhD

Michael A. Wheeler, PhD
Assistant Professor of Neurology
Ann Romney Center for Neurologic Diseases
Brigham and Women’s Hospital
Harvard Medical School
The Broad Institute
Boston, MA | USA

The objective of my research program is to study brain-immune interactions that control behavior and neuropsychiatric diseases, also asking how these processes are shaped in the context of aging and tissue inflammation. Along these lines, my lab aims to identify novel mechanisms and develop new tools to study the molecular mechanisms regulating cross-talk among structural cells in the brain called glia, brain circuits, and the immune system. To address these questions my lab uses mouse genetics, genomics (and other ‘omics), mouse behavior, actuator technologies, and human samples as well as new single-cell and molecular genetic tools that we developed to study neuroimmune communication.